Applied Nutrition - Citrulline Malate 2:1 - 300g 100 Servings

Name: Applied Nutrition - Citrulline Malate 2:1 - 300g 100 Servings
Brand: Applied Nutrition
SKU: 5056555206706
Price: 11.99 GBP
Availability: InStock

Applied Nutrition - Citrulline Malate 2:1 - 300g 100 Servings

£11.99

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Description
How & when to use
Nutritional information
References

Description

Citrulline Malate 2:1 is a synergistic blend of L-Citrulline and malic acid designed to support performance during high-intensity training. L-Citrulline is a non-essential amino acid that plays a critical role in the urea cycle and nitric oxide (NO) production pathway. Research shows that oral supplementation with L-Citrulline increases plasma arginine levels more effectively than L-arginine itself [1], resulting in enhanced nitric oxide synthesis.

Nitric oxide promotes vasodilation, improving blood flow to working muscles during exercise. This mechanism has been associated with improved endurance, oxygen delivery, and nutrient transport [2]. Additionally, studies have reported that Citrulline Malate supplementation may reduce perceived exertion and delay fatigue in both aerobic and anaerobic performance contexts [3][4].

The 2:1 ratio represents two parts L-Citrulline to one part malic acid, which is an intermediate in the Krebs cycle. Malic acid may contribute to the compound’s ability to support energy metabolism, though more research is needed to substantiate this claim in isolation [5].

Suitable for vegetarians & vegans
100 servings per container

How & when to use

Mix 1 scoop (3g) with water, juice, pre workout, or your preferred beverage. Consume once daily.

For best results use 30 minutes prior to workout.

Nutritional information

Serving size: 1 scoop (3g)

Values	Per serving
Citrulline Malate 2:1	3000mg

Servings per container: 100

References

Schwedhelm, E., et al. (2008). "Pharmacokinetics and bioavailability of oral L-citrulline compared to L-arginine." British Journal of Clinical Pharmacology, 65(1), 51–59. https://doi.org/10.1111/j.1365-2125.2007.02990.x
Bailey, S. J., et al. (2015). "Effects of L-citrulline supplementation on oxygen uptake kinetics and high-intensity exercise performance in humans." Amino Acids, 47, 1793–1801. https://doi.org/10.1007/s00726-014-1809-9
Pérez-Guisado, J., & Jakeman, P. M. (2010). "Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness." Journal of Strength and Conditioning Research, 24(5), 1215–1222. https://doi.org/10.1519/JSC.0b013e3181c6a185
Wax, B., et al. (2016). "Effects of L-citrulline supplementation on muscle soreness and performance recovery after intense exercise in older adults." European Journal of Applied Physiology, 116, 2025–2034. https://doi.org/10.1007/s00421-016-3445-x
Sureda, A., et al. (2017). "Oral administration of L-citrulline reduces muscle soreness and enhances aerobic performance in rats." Nutrients, 9(9), 949. https://doi.org/10.3390/nu9090949